Kidney Problems and NSF
Nephrogenic systemic fibrosis (NSF), also known as nephrogenic fibrosing dermopathy (NFD) is a rare debilitating condition. Patients with NSF develop large areas of hardened skin, plaques, and fibrosis of the joints, eyes, and internal organs. There is no known cure for the disorder, only experimental treatments and treatments to help alleviate some of the symptoms. NSF has only ever been observed in patients that also have kidney problems.
Causes of Nephrogenic Systemic Fibrosis
NSF can occur after a patient with a kidney disorder undergoes an MRI scan to search for other problems. During the scan, patients ingest a gadolinium-based contrast agent so that the image can appear and the problem, such as a tumor, can be identified.
In patients without kidney disorders, the gadolinium-based agent is safely flushed from the body a few hours after the MRI procedure. However, in patients with kidney problems, this removal of toxins does not occur. As a result, gadolinium can collect in the body and cause the adverse effects known as nephrogenic systemic fibrosis.
MRI Contrast Agents
NSF has been associated with gadolinium-based contrast agents used in MRI scans, including:
- Omniscan
- Multihance
- Magnevist
- OptiMARK
If you need an MRI and have a pre-existing kidney condition, be sure to speak with your doctor about your options and alternatives.
Contact Us
If you or a loved one has been diagnosed with a gadolinium-related disorder, contact the gadolinium attorneys of Williams Kherkher by calling 800-761-3187.